Wiped film distillation purifies cannabis crude oil to 90-95% total cannabinoids by spreading a sub-1mm film across a heated cylinder at 160-180°C under sub-100-micron vacuum. Residence time is 1-3 minutes (vs 10-60 minutes in short path), reducing thermal CBN formation from 4% to under 0.5%. A 2-inch Pope system processes 500-800 mL/hour at 30% rotor [...]
Building an extraction laboratory is one of the biggest investments you will make in the cannabis or hemp industry. Get it right, and you have a production pipeline that generates consistent, high-quality products for years. Get it wrong, and you are looking at wasted capital, compliance headaches, and products that never meet market standards. This [...]
What Is Remediation in Cannabis Processing? When a cannabis batch fails testing, should you remediate it or destroy it? This is one of the most expensive decisions an extraction operator faces, and most people make it based on gut feeling rather than chemistry. Remediation is the process of bringing a non-compliant cannabis product back into [...]
Stop Fighting Kinetics: A Three-Stage Route to ∆9-THC via Regioselective Elimination CBD ISOMERIZATION HOW TO: The Problem Every Scale-Up Chemist Knows:If you have ever run an acid-catalyzed cyclization of CBD in a 50L reactor and pulled HPLC results showing a 5:1 ∆8:∆9 ratio, you already understand the frustration. The textbooks promise that lower temperature favors [...]
Learn how to make a 1-liter cannabis nano emulsion in your lab. Step-by-step SOP covering premix ratios, sonication parameters, and shelf stability tips.
Learn how to make live resin from fresh frozen cannabis. Expert guide covering flash freezing, propane-heavy solvent blends, extraction temps, and lab setup.
What Is a Closed Loop BHO Extraction System? A closed loop BHO extraction system is the industry standard for professional hydrocarbon cannabis and hemp extraction. Unlike open blasting methods, a closed loop system contains all solvents within a sealed circuit, recovering and recycling butane and propane throughout the process. This makes it safer, more efficient, [...]
What Is Color Remediation Chromatography? Color remediation chromatography (CRC) is a post-extraction purification technique that uses layered adsorbent media in a pressurized column to selectively remove pigments, chlorophyll, carotenoids, and other color-causing impurities from cannabis extracts. Originally adapted from the edible oil refining industry: where magnesium silicate and activated carbon have been used for decades [...]
Artificial intelligence is reshaping how chemistry labs operate, and the cannabis and hemp industry is no exception. From routine data logging to complex analytical decision-making, AI-driven automation is eliminating bottlenecks that have plagued extraction and post-processing labs for years. Where AI Fits in Lab Operations The most immediate impact is in instrument integration and data [...]
Cannabinoid Biosynthesis Is Changing Everything Cannabinoid biosynthesis is no longer a theoretical concept confined to academic papers â it's an industrial reality that's forcing the entire cannabis industry to pay attention. Scientists have successfully engineered yeast to produce THC, CBD, and rare cannabinoids like THCV and CBGV from nothing more than simple sugars. No plants. [...]
